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Fast weight loss: which ones work and which ones to avoid

There are many ways to lose weight today. Of these, however, only a few are really effective, but you always need commitment, perseverance,  and a lot of patience. In fact, weight loss takes time and even if there are solutions that promise to lose weight in a short time, you have to be very careful, because they could be harmful to your health. We must bear in mind that shortcuts can be dangerous and jeopardize the well-being of the body. Slimming drugs can have contraindications that should not be underestimated. In addition, losing weight drastically carries significant risks. Therefore, as obvious as it may seem, the best way to lose weight and have lasting results is to have a healthy and balanced diet combined with some physical exercise. Different speech, however, for supplements. The latter is hardly harmful to the deficiencies in vitamins, fibers,  and other nutrients, due to a more restrictive diet.

Why always seek the opinion of your doctor?

If you are considering taking weight loss medications or supplements, always talk to your doctor first, especially if you have any health problems or are on medications. In fact, your doctor is the only person who can follow you in planning your food plan and keep your progress under control. In addition, your doctor will be able to tell you with certainty any side effects and symptoms to pay particular attention to. Many diet drugs contain several active ingredients that can interact with the drugs which they usually take. If you regularly take medications or herbal supplements, taking weight-loss drugs at the same time can be dangerous.

Slimming substances to avoid

Until recently, there were only two approved weight loss drugs, sibutramine pills and orlistat pills. Sibutramine-based slimming pills were recommended in cases of obesity, as they helped stimulate the sense of satiety and, therefore, reduced food consumption. Furthermore, it increases thermogenesis with a mechanism of action very similar to those of ephedrine, a natural active ingredient useful for weight loss, but no longer marketable. The side effects of sibutramine are various, among these, there are some of cardiovascular nature, such as tachycardia, palpitations, and hypertension. For this very reason, these pills were not recommended for patients suffering from heart or cardiovascular problems. As of January, the drug was once again banned from the market, as the side effects outweighed the benefits. Orlistat-based pills, on the other hand, work by reducing the absorption of dietary fat. Taking these pills can cause flatulence, fecal urgency and oily deletions, especially after meals particularly rich in lipids. There are also other drugs with a slimming effect on the market, but they have not been approved for this purpose. Among these are those based on thyroid hormones such as eutirox and its analogs. Drugs banned for their serious side effects, but still available on the black market, including amphetamines and phenylpropanolamine. In general, all slimming drugs can have important side effects, especially in case of abuse, such as thyroid dysfunction, and pulmonary and cardiac complications. Different speech, however, for supplements, as they can be really useful for integrating your food plan. However, even these can have contraindications. They cannot be taken in case of being underweight, as they could have dangerous effects on health. They are not indicated in case of pregnancy, since in this particular moment for women it is always better to take only supplements following the doctor's instructions. Furthermore, in the presence of certain pathologies or if you are taking medicines, it is always better to consult your doctor first.

The most common side effects were recorded at the gastrointestinal level, such as nausea, diarrhea, vomiting, and constipation, which increased as the dosage increased. The most common were nausea, affecting 24.6 percent of patients receiving the 5-milligram dose and more than 30 percent of those receiving the 10- and 15-milligram dose. Diarrhea also affected about 1 in 5 patients, while vomiting and constipation affected 1 in 10. The scientists point out that the safety profile, with mild to moderate side effects, was “similar to other drug-based therapies incretin approved for the treatment of obesity”. The discontinuation rate due to adverse events was 4.3 percent for the 5-milligram dose; 7.1 percent for the 10-milligram one; and 6.2 percent for the 15-milligram one. The research findings have not been peer-reviewed at this time and will be submitted to a scientific journal shortly. The results of additional studies on the drug's efficacy and safety are expected within the next year. Only subsequently will the approval of tripeptide as a therapy for the treatment of obesity be requested. According to a recent study, almost a quarter of Europeans are considered obese.

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